The Mute Tool is used for muting clips in the arrangement - or lanes in Block automation clips (see “Muting lanes in Block Automation Clips”).
The Speaker Tool is used for auditioning slices or notes in Single Take audio clips, and for auditioning individual recordings on Comp Rows in Comp Clips. See “Slice Edit mode tools”, “Auditioning notes” and “Comp Editor audio editing tools” for details.
However, there’s one exception: If a note clip is open in Edit Mode and you click in the Clip Overview (see “Edit Mode elements”), the clip will remain open but the Snap value for arranging will be selected. This allows you to e.g. move or resize the clip in the Clip Overview just like in the Song/Blocks View, without closing it first.
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